{"id":81939,"date":"2022-09-09T15:39:20","date_gmt":"2022-09-09T13:39:20","guid":{"rendered":"https:\/\/www.wholecelium.com\/?p=81939"},"modified":"2023-05-12T16:08:17","modified_gmt":"2023-05-12T14:08:17","slug":"3-of-the-most-exciting-upcoming-microdosing-studies","status":"publish","type":"post","link":"https:\/\/staging.wholecelium.com\/cs\/blog\/3-z-nejzajimavejsich-nadchazejicich-mikrodoznich-studii\/","title":{"rendered":"3 nejzaj\u00edmav\u011bj\u0161\u00ed nadch\u00e1zej\u00edc\u00ed studie mikrod\u00e1vkov\u00e1n\u00ed"},"content":{"rendered":"

Vyvol\u00e1 zm\u011bny v legislativ\u011b, zbo\u0159\u00ed p\u0159edsudky a zm\u011bn\u00ed \u017eivoty lid\u00ed trp\u00edc\u00edch poruchami, kter\u00e9 doned\u00e1vna nebylo mo\u017en\u00e9 \u00fa\u010dinn\u011b l\u00e9\u010dit.\u00a0<\/strong><\/p>\n\n\n\n

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Foto: Moritz Kindler on Unsplash<\/em><\/figcaption><\/figure>\n\n\n\n

V\u00fdzkum pokra\u010duje...<\/h2>\n\n\n\n

A studie st\u00e1le p\u0159ich\u00e1zej\u00ed a nep\u0159est\u00e1vaj\u00ed p\u0159ich\u00e1zet. Dnes se v\u0161ak pod\u00edv\u00e1me na n\u011bkolik nadch\u00e1zej\u00edc\u00edch psilocybinov\u00fdch (a n\u011bkter\u00e9 z jeho dal\u0161\u00edch psychedelick\u00fdch sourozenc\u016f, jako nap\u0159. LSD<\/a>)<\/em> zkou\u0161ek, kter\u00e9 m\u00e1me dobr\u00e9 <\/em>pocit o. A jsou nepr\u016fst\u0159eln\u00e9 - dvojit\u011b zaslepen\u00e9, placebem kontrolovan\u00e9 - \u00fapln\u00e1 par\u00e1da. Tak si je poj\u010fme vyzkou\u0161et!<\/p>\n\n\n\n

Mikrod\u00e1vky psilocybinu u perzistentn\u00ed depresivn\u00ed poruchy<\/h2>\n\n\n\n

V lednu leto\u0161n\u00edho roku, Zdrav\u00ed vl\u00e1ken<\/a>, psychedelick\u00e1 spole\u010dnost ozn\u00e1mila kanadskou spolupr\u00e1ci s Torontskou univerzitou. F\u00e1ze 2 klinick\u00e9 studie o \u00fa\u010dinku mikrod\u00e1vek psilocybinu na perzistentn\u00ed depresivn\u00ed poruchu. Zah\u00e1jen\u00ed je napl\u00e1nov\u00e1no na druhou polovinu roku a p\u016fjde o jednu z prvn\u00edch \u0159\u00e1dn\u011b kontrolovan\u00fdch studi\u00ed, kter\u00e9 uvid\u00edme ohledn\u011b mikrod\u00e1vkov\u00e1n\u00ed jako l\u00e9\u010dby deprese.<\/p>\n\n\n\n

Pokud studie zjist\u00ed, \u017ee mikrod\u00e1vkov\u00e1n\u00edm lze \u00fasp\u011b\u0161n\u011b l\u00e9\u010dit depresi, bude to vynikaj\u00edc\u00ed zpr\u00e1va pro miliony lid\u00ed na cel\u00e9m sv\u011bt\u011b, kte\u0159\u00ed u\u017e\u00edvaj\u00ed antidepresiva, v\u010detn\u011b 13% v\u0161ech Ameri\u010dan\u016f. A\u010dkoli se trad farmaceutick\u00e9 p\u0159\u00edpravky do <\/em>u \u010d\u00e1sti pacient\u016f funguj\u00ed, u mnoha ne. A pro n\u011bkter\u00e9 vedlej\u0161\u00ed \u00fa\u010dinky nestoj\u00ed za bolest.<\/p>\n\n\n\n

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Foto: Gadiel Lazcano on Unsplash<\/em><\/figcaption><\/figure>\n\n\n\n

Do t\u00e9to specifick\u00e9 studie bylo za\u0159azeno 50 pacient\u016f s perzistentn\u00ed depresivn\u00ed poruchou. Polovina skupiny dostala 2 mg psilocybinu a druh\u00e1 polovina placebo. To se bude d\u00edt jednou t\u00fddn\u011b po dobu 4 t\u00fddn\u016f. Po skon\u010den\u00ed tohoto obdob\u00ed studie budou v\u0161ichni pacienti, v\u010detn\u011b t\u011bch, kte\u0159\u00ed dost\u00e1vali placebo, dost\u00e1vat l\u00e9\u010dbu dal\u0161\u00ed 4 t\u00fddny. Dr\u017eme si palce, abychom n\u011bjak\u00e9 \u00fadaje z t\u00e9to studie m\u011bli na dosah do konce roku 2023. <\/p>\n\n\n\n

Mikrod\u00e1vka LSD pro dosp\u011bl\u00e9 s ADHD<\/h2>\n\n\n\n

Mikrod\u00e1vkov\u00e1n\u00ed psilocybinu bylo n\u011bjakou dobu propagov\u00e1no jako slibn\u00e1 podpora<\/a> pro dosp\u011bl\u00e9 s ADHD. Nicm\u00e9n\u011b tato studie spole\u010dnosti MindMed<\/a>, ozn\u00e1men\u00e1 v prosinci 2021, bude pro sv\u00e9 mikrod\u00e1vky pou\u017e\u00edvat LSD. Jedn\u00e1 se o sv\u011btov\u00fd unik\u00e1t - studii f\u00e1ze 2 l\u00e9\u010dby ADHD pomoc\u00ed psychedelika. St\u00e1le v\u00edce dosp\u011bl\u00fdch dost\u00e1v\u00e1 diagn\u00f3zu ADHD, proto\u017ee se o tomto onemocn\u011bn\u00ed za\u010d\u00edn\u00e1 v\u00edce v\u011bd\u011bt. <\/p>\n\n\n\n

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Foto: Drew Dizzy Graham on Unsplash<\/em><\/figcaption><\/figure>\n\n\n\n

Na\u0161t\u011bst\u00ed se uv\u00e1d\u011bn\u00e9 \u00fa\u010dinky mikrod\u00e1vek psychedelik p\u0159esn\u011b shoduj\u00ed s t\u00edm, s \u010d\u00edm se pot\u00fdkaj\u00ed lid\u00e9 s ADHD. Mnoho dosp\u011bl\u00fdch s ADHD m\u00e1 nap\u0159\u00edklad pot\u00ed\u017ee se soust\u0159ed\u011bn\u00edm nebo koncentrac\u00ed - co\u017e je p\u0159esn\u011b jedna z v\u011bc\u00ed, s nimi\u017e m\u00e1 mikrod\u00e1vkov\u00e1n\u00ed pomoci. N\u00e1ladu zlep\u0161uj\u00edc\u00ed a uklid\u0148uj\u00edc\u00ed \u00fa\u010dinky mikrod\u00e1vek mohou tak\u00e9 pomoci zm\u00edrnit neklid a podr\u00e1\u017ed\u011bnost, kter\u00fdmi lid\u00e9 s ADHD \u010dasto trp\u00ed. <\/p>\n\n\n\n

To jsou jen n\u011bkter\u00e9 z hypot\u00e9z, kter\u00e9 chce tato studie prok\u00e1zat. Douf\u00e1me tak\u00e9, \u017ee pokud bude tato studie \u00fasp\u011b\u0161n\u00e1, otev\u0159e LSD cestu k pou\u017eit\u00ed jako l\u00e9ku na ADHD - v\u00edtan\u00e9 alternativ\u011b k tradi\u010dn\u00edm l\u00e9k\u016fm na ADHD, kter\u00e9 jsou \u010dasto stimulanty s mo\u017enost\u00ed vzniku z\u00e1vislosti. <\/p>\n\n\n\n

Studie se z\u00fa\u010dastn\u00ed 52 dosp\u011bl\u00fdch s ADHD. Ti budou dost\u00e1vat 20 mikrogram\u016f LSD nebo placebo 2x t\u00fddn\u011b po dobu 6 t\u00fddn\u016f. Prvn\u00ed \u00fadaje z t\u00e9to studie se o\u010dek\u00e1vaj\u00ed v druh\u00e9 polovin\u011b roku 2023. <\/p>\n\n\n\n

Prob\u00edhaj\u00edc\u00ed projekt Microdose.me<\/h2>\n\n\n\n

M\u00e1me jmenovit\u011b<\/a> Microdose.me d\u0159\u00edve - v\u017edy\u0165 jde o nejv\u011bt\u0161\u00ed mobiln\u00ed studii mikrod\u00e1vkov\u00e1n\u00ed na sv\u011bt\u011b! Na str\u00e1nk\u00e1ch aplikace<\/a>, poh\u00e1n\u011bn\u00fd syst\u00e9mem Quantified Citizen, lze jednodu\u0161e pou\u017e\u00edt k zaznamen\u00e1v\u00e1n\u00ed rutinn\u00edch mikrod\u00e1vek a jejich \u00fa\u010dink\u016f. Nicm\u00e9n\u011b u psilocybinu t\u011b\u017ek\u00e9 v\u00e1hy Paul Stamets<\/a>, a l\u00e9ka\u0159\u0161t\u00ed v\u00fdzkumn\u00edci, jako jsou Dr. Pamela Kryskow a Dr. Zach Walsh, jako sou\u010d\u00e1st t\u00fdmu, budou data, kter\u00e1 shrom\u00e1\u017ed\u00ed ve spolupr\u00e1ci s u\u017eivateli aplikace, pou\u017eita k dosa\u017een\u00ed pokroku ve v\u00fdzkumu mikrod\u00e1vkov\u00e1n\u00ed. A tak\u00e9 ji\u017e maj\u00ed<\/strong>. Od zah\u00e1jen\u00ed studie na konci roku 2019 se do n\u00ed zapojilo v\u00edce ne\u017e 20 000 \u00fa\u010dastn\u00edk\u016f z 84 zem\u00ed a mnoho zji\u0161t\u011bn\u00ed ji\u017e bylo zve\u0159ejn\u011bno. Ve skute\u010dnosti teprve p\u0159ed n\u011bkolika m\u011bs\u00edci vydali na z\u00e1klad\u011b \u00fadaj\u016f z aplikace publikaci. <\/p>\n\n\n\n

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Foto: DocuSign on Unsplash<\/em><\/figcaption><\/figure>\n\n\n\n

Zve\u0159ejn\u011bno dne nature.com<\/a> 30. \u010dervna v\u00fdzkum uk\u00e1zal, \u017ee u u\u017eivatel\u016f, kte\u0159\u00ed u\u017e\u00edvali psilocybin v mikrod\u00e1vk\u00e1ch po dobu 30 dn\u016f, do\u0161lo k v\u011bt\u0161\u00edmu zlep\u0161en\u00ed du\u0161evn\u00edho zdrav\u00ed, n\u00e1lady a psychomotorick\u00fdch schopnost\u00ed ve srovn\u00e1n\u00ed s t\u011bmi, kte\u0159\u00ed mikrod\u00e1vky neu\u017e\u00edvali. Zlep\u0161en\u00ed psychomotorick\u00fdch schopnost\u00ed bylo zvl\u00e1\u0161t\u011b v\u00fdznamn\u00e9 u mikrod\u00e1vkuj\u00edc\u00edch, kter\u00fdm bylo v\u00edce ne\u017e 55 let. (v porovn\u00e1n\u00ed s t\u011bmi, kte\u0159\u00ed nejsou mikrodosery.)<\/em> To uk\u00e1zalo obrovsk\u00fd potenci\u00e1l pro nov\u00fd v\u00fdzkum psilocybinu k l\u00e9\u010db\u011b. neurodegenerativn\u00ed onemocn\u011bn\u00ed<\/a>, pro kter\u00e9 bude jist\u011b n\u00e1sledovat dal\u0161\u00ed v\u00fdzkum. <\/p>\n\n\n\n

Nov\u00fd dokument b\u011bhem n\u011bkolika t\u00fddn\u016f<\/h3>\n\n\n\n

Skv\u011bl\u00e9 na microdose.me je, \u017ee jsou schopni publikovat dokumenty, zat\u00edmco prob\u00edhaj\u00edc\u00ed v\u00fdzkum pokra\u010duje. Modern\u00ed technologie, \u017ee?! A jak Paul Stamets prozradil magaz\u00ednu Doubleblind, brzy se objev\u00ed dal\u0161\u00ed poznatky. \u010cl\u00e1nek m\u00e1 b\u00fdt p\u0159edlo\u017een v \u010dasopise \"...asi dva t\u00fddny do dvou recenzovan\u00fdch \u010dasopis\u016f.<\/em>.\" Tak\u00e9 n\u00e1s po\u0161k\u00e1dlil l\u00e1kav\u00fdm cit\u00e1tem;<\/p>\n\n\n\n

\"Jedn\u00e1 se o jednu z nejsiln\u011bj\u0161\u00edch studi\u00ed v historii l\u00e9ka\u0159sk\u00fdch klinick\u00fdch studi\u00ed. Byli jsme \u0161okov\u00e1ni. Nikdo z na\u0161ich v\u00fdzkumn\u00edk\u016f neo\u010dek\u00e1val, \u017ee \u00fadaje budou tak dobr\u00e9. Mysleli jsme si, \u017ee uvid\u00edme mal\u00e9 zlep\u0161en\u00ed, ale ne tak vysok\u00e9 zlep\u0161en\u00ed oproti v\u00fdchoz\u00edmu stavu. Nyn\u00ed v\u00edme, \u017ee mikrod\u00e1vkov\u00e1n\u00ed psilocybinov\u00fdch hub funguje. Je nesporn\u00e9, \u017ee to m\u00e1 p\u0159\u00ednos.\"<\/em><\/p>\n\n\n\n

Z\u00edskejte v\u0161echny psychedelick\u00e9 aktualizace zde!<\/h2>\n\n\n\n
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Foto: Landon Parenteau on Unsplash<\/em><\/figcaption><\/figure>\n\n\n\n

Je\u017e\u00ed\u0161marj\u00e1! Milujeme psychedelick\u00fd v\u00fdzkum. Je to dar, kter\u00fd se st\u00e1le rozd\u00e1v\u00e1. A vy se m\u016f\u017eete spolehnout, \u017ee v\u00e1s budeme z\u00e1sobovat novinkami, jakmile se objev\u00ed!  <\/p>","protected":false},"excerpt":{"rendered":"

R\u00e1di sledujeme v\u0161echny pokroky ve v\u00fdzkumu psychedelik. A\u0165 u\u017e se jedn\u00e1 o studie, kter\u00e9 ukazuj\u00ed, \u017ee psilocybin je \u00fa\u010dinn\u011bj\u0161\u00ed ne\u017e standardn\u00ed antidepresiva Velk\u00e9 farmaceutick\u00e9 spole\u010dnosti, nebo jin\u00e9, kter\u00e9 zkoumaj\u00ed vyu\u017eit\u00ed psilocybinu k l\u00e9\u010db\u011b vyho\u0159en\u00ed, j\u00edm\u017e trp\u00ed na\u0161i z\u00e1kladn\u00ed zdravotni\u010dt\u00ed pracovn\u00edci, je to v\u0161echno fascinuj\u00edc\u00ed cesta do budoucnosti du\u0161evn\u00ed p\u00e9\u010de.<\/p>","protected":false},"author":1,"featured_media":81957,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[88],"tags":[],"topics":[],"class_list":["post-81939","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-psychedelic-studies"],"_links":{"self":[{"href":"https:\/\/staging.wholecelium.com\/cs\/wp-json\/wp\/v2\/posts\/81939","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/staging.wholecelium.com\/cs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/staging.wholecelium.com\/cs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/staging.wholecelium.com\/cs\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/staging.wholecelium.com\/cs\/wp-json\/wp\/v2\/comments?post=81939"}],"version-history":[{"count":4,"href":"https:\/\/staging.wholecelium.com\/cs\/wp-json\/wp\/v2\/posts\/81939\/revisions"}],"predecessor-version":[{"id":124079,"href":"https:\/\/staging.wholecelium.com\/cs\/wp-json\/wp\/v2\/posts\/81939\/revisions\/124079"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/staging.wholecelium.com\/cs\/wp-json\/wp\/v2\/media\/81957"}],"wp:attachment":[{"href":"https:\/\/staging.wholecelium.com\/cs\/wp-json\/wp\/v2\/media?parent=81939"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/staging.wholecelium.com\/cs\/wp-json\/wp\/v2\/categories?post=81939"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/staging.wholecelium.com\/cs\/wp-json\/wp\/v2\/tags?post=81939"},{"taxonomy":"topics","embeddable":true,"href":"https:\/\/staging.wholecelium.com\/cs\/wp-json\/wp\/v2\/topics?post=81939"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}